https://www.mdu.se/

mdu.sePublications
Change search
Refine search result
1 - 16 of 16
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Rows per page
  • 5
  • 10
  • 20
  • 50
  • 100
  • 250
Sort
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
Select
The maximal number of hits you can export is 250. When you want to export more records please use the Create feeds function.
  • 1.
    Backström, Tomas
    et al.
    Mälardalen University, School of Innovation, Design and Engineering.
    Strömberg, Anette
    Mälardalen University, School of Innovation, Design and Engineering.
    Sjödin, Carina
    Mälardalen University, School of Innovation, Design and Engineering.
    Shared vision as an order parameter2010In: Society for chaos in psychology and life sciences international conference, Palermo, 2010Conference paper (Refereed)
    Abstract [en]

    This paper is dealing with a way to temporarily change the patterns of thinking and acting of a team. Or more specific; to move a team through a phase transition from an ordered phase to a complex phase. The aim is to make it possible for production personnel to contribute and be integrated in idea development processes. Innovation and improvement are important to ensure long term competitiveness for most companies. Since patterns of thinking and acting in idea development is different from the ones needed in production it is often recommended to perform this work in a department not connected to production. The division between production and idea development may lead to several problems; e.g. impoverishment of the work of production personnel, no input from common days experience in idea development, and harder for production personnel to understand and take responsibility for the production of new products resulting from the idea development, and thus e.g. hamper future work with improvements of it. The ideal for team creativity is to be able to make use of all members' different ideas, experiences and different ways to understand things, in a common creative process. This is possible if each team member at the same time is both autonomous, independently using its competence in action, and integrated, relating each action to an emerging idea shared by all team members. When independent agents interact, and an organization which controls the actions of the agents emerges in this interaction, then we have a complex system, by definition. The agents are at the same time autonomous, following their individual organization, and integrated to the system, following the organization of the system. Most of the work tasks for normal teams in work life demands predictability, not creativity. Such teams develop patterns of thinking and acting that is good for repeatedly producing with high efficiency and quality. This is possible for an ordered system with low autonomy, not a complex system. The question of this paper is: Is it possible to find a strategy that may be used to support a team to reach a complex phase, were it is creative sooner than predictable? An important inspiration writing this paper has been an article Movie making as a mediator in dialogue (Palus & Drath). The thoughts presented in the article were similar to our understanding of how to support creativity of teams and we have decided to use this technique in our creativity lab. In our paper we describe how to understand this technique from a complexity perspective, and start a discussion about how to measure the complexity of a team's social interaction.

  • 2.
    Bojesson, Catarina
    et al.
    Mälardalen University, School of Innovation, Design and Engineering, Innovation and Product Realisation.
    Jackson, Mats
    Mälardalen University, School of Innovation, Design and Engineering, Innovation and Product Realisation.
    Strömberg, Anette
    Mälardalen University, School of Innovation, Design and Engineering, Innovation and Product Realisation.
    Rethinking effectiveness: Addressing managerial paradoxes by using a process perspective on effectiveness2014Conference paper (Refereed)
  • 3.
    Carlsson, Anna-Lena
    et al.
    Mälardalen University, School of Innovation, Design and Engineering, Innovation and Product Realisation. IPR (Innovation and Product Realisation).
    Bengtsson, Marcus
    Mälardalen University, School of Innovation, Design and Engineering, Innovation and Product Realisation. IPR (Innovation and Product Realisation).
    Fundin, Anders
    Mälardalen University, School of Innovation, Design and Engineering, Innovation and Product Realisation. IPR (Innovation and Product Realisation).
    Jackson, Mats
    Mälardalen University, School of Innovation, Design and Engineering, Innovation and Product Realisation. IPR (Innovation and Product Realisation).
    Strömberg, Anette
    Mälardalen University, School of Innovation, Design and Engineering, Innovation and Product Realisation. IPR (Innovation and Product Realisation).
    Phases of Co-Production: Follow-up Research on the Industrial Research School INNOFACTURE2015Conference paper (Refereed)
    Abstract [en]

    Mälardalen Univerity is characterised by its close collaboration with companies and with the public sector in the region. A main strategic directions of the university is to develop co-production with partner companies, expressed in the university vision “A Strong MDH – the Coproducing University”. The concept ’co-production’ is in this paper used interchangeably with concept ’co-creation’, emphasising our view of equal participation and interaction with the goal of knowledge, that by the company can be made useful outside the university (see Terblanche, 2014). Based on Mälardalen University’s vision, co-production is a main goal for the Innovation and Product Realization (IPR) environment. IPR is located at the School of Innovation, Design and Engineering and has a common graduate education with three mutually supportive cooperating research groups: Product realization, Innovation management, and Information design. Here ideas from different fields and cultures meet, creating new ideas, possibilities, and knowledge as a result. The approach to develop new insights and knowledge in order to address societal challenges, through working closer between academics and research users, has a potential to improve how research is conducted. Still, there are many questions and challenges in this approach, with need of development: How is research and research education framed and undertaken? What constitutes co-production? What distinguishes reseach in co-production from other forms of research? What are the benefits and barriers of co-production? As we shall see, the follow-up research aim to contribute to how our third level education in a co-production environment can be undertaken.

  • 4.
    Chiu, D T
    et al.
    Univ. of Washington, United States.
    Davidson, M
    Goteborg Univ..
    Strömberg, Anette
    Mälardalen University, School of Innovation, Design and Engineering, Innovation and Product Realisation. Goteborg Univ..
    Ryttsen, F
    Goteborg Univ..
    Orwar, O
    Goteborg Univ..
    Electrical and optical methods for the manipulation and analyses of single cells2001In: CLINICAL DIAGNOSTIC SYSTEMS / [ed] Cohn, G E, Univ Washington, Dept Chem, Seattle, WA 98195 USA.: SPIE-INT SOC OPTICAL ENGINEERING , 2001, p. 1-8Conference paper (Refereed)
    Abstract [en]

    This paper describes the use of focused electric fields and focused optical fields for the high resolution manipulation of single cells. A focused electric field, obtained with the use of ultramicroelectrodes (tip diameter similar to 5 mum), is used to electroporate and electrofuse individual cells selectively and with high spatial resolution. A focused optical field, in the form of an optical tweezer, is used to isolate single organelles from a cell as well as to position liposomes incorporated with receptors and transporters along the cell for the high-resolution sampling and probing of the cellular microenvironment.

  • 5. Chiu, D T
    et al.
    Wilson, C F
    Karlsson, A
    Danielsson, A
    Lundqvist, A
    Strömberg, Anette
    Göteborg University, Göteborg, Sweden.
    Ryttsen, F
    Davidson, M
    Nordholm, S
    Orwar, O
    Zare, R N
    Manipulating the biochemical nanoenvironment around single molecules contained within vesicles1999In: Chemical Physics, ISSN 0301-0104, E-ISSN 1873-4421, Vol. 247, no 1, p. 133-139Article in journal (Refereed)
    Abstract [en]

    A method to study single-molecule reactions confined in a biomimetic container is described. The technique combines rapid vesicle preparation, optical trapping and fluorescence confocal microscopy for performing simultaneous single-vesicle trapping and single-molecule detection experiments. The collisional environment between a single enzyme and substrate inside a vesicle is characterized by a Brownian dynamics Monte Carlo simulation. (C) 1999 Elsevier Science B.V. All rights reserved.

  • 6. Chiu, D T
    et al.
    Wilson, C F
    Ryttsen, F
    Strömberg, Anette
    Göteborg University, Sweden.
    Farre, C
    Karlsson, A
    Nordholm, S
    Gaggar, A
    Modi, B P
    Moscho, A
    Garza-Lopez, R A
    Orwar, O
    Zare, R N
    Chemical transformations in individual ultrasmall biomimetic containers1999In: Science, ISSN 0036-8075, E-ISSN 1095-9203, Vol. 283, no 5409, p. 1892-1895Article in journal (Refereed)
    Abstract [en]

    Individual phospholipid vesicles, 1 to 5 micrometers in diameter, containing a single reagent or a complete reaction system, were immobilized with an infrared laser optical trap or by adhesion to modified borosilicate glass surfaces. Chemical transformations were initiated either by electroporation or by electrofusion, in each case through application of a short (10-microsecond), intense (20 to 50 kilovolts per centimeter) electric pulse delivered across ultramicroelectrodes. Product formation was monitored by far-field laser fluorescence microscopy. The ultrasmall characteristic of this reaction volume led to rapid diffusional mixing that permits the study of fast chemical kinetics. This technique is also well suited for the study of reaction dynamics of biological molecules within lipid-enclosed nanoenvironments that mimic cell membranes.

  • 7.
    Karlsson, Anders
    et al.
    Gothenburg University, Sweden.
    Karlsson, Roger
    Gothenburg University, Sweden.
    Karlsson, Mattias
    Gothenburg University, Sweden.
    Cans, Annsofie
    Gothenburg University, Sweden.
    Strömberg, Anette
    Gothenburg University, Sweden.
    Ryttsén, Frida
    Gothenburg University, Sweden.
    Orwar, Owe
    Chalmers University of Technology, Sweden.
    Molecular engineering: Networks of nanotubes and containers2001In: Nature, ISSN 0028-0836, E-ISSN 1476-4687, Vol. 409, no 6817, p. 150-152Article in journal (Refereed)
  • 8.
    Karlsson, M
    et al.
    Department of Chemistry, Göteborg University.
    Nolkrantz, K
    Department of Chemistry, Göteborg University.
    Davidson, M J
    Department of Chemistry, Göteborg University.
    Strömberg, Anette
    Department of Chemistry, Göteborg University.
    Ryttsen, F
    Department of Chemistry, Göteborg University.
    Akerman, B
    Department of Chemistry, Göteborg University.
    Orwar, O
    Department of Chemistry, Göteborg University.
    Electroinjection of colloid particles and biopolymers into single unilamellar liposomes and cells for bioanalytical applications2000In: Analytical Chemistry, ISSN 0003-2700, E-ISSN 1520-6882, Vol. 72, no 23, p. 5857-5862Article in journal (Refereed)
    Abstract [en]

    A combined electroporation and pressure-driven microinjection method for efficient loading of biopolymers and colloidal particles into single-cell-sized unilamellar liposomes was developed. Single liposomes were positioned between a similar to2-mum tip diameter solute-filled glass micropipet, equipped with a Pt electrode, and a 5-mum-diameter carbon fiber electrode. A transient, 1-10 ms, rectangular waveform de voltage pulse (10-40 V/cm) was applied between the electrodes, thus focusing the electric field over the liposome. Dielectric membrane breakdown induced by the applied voltage pulse caused the micropipet tip to enter the liposome and a small volume (typically 50-500 x 10(-15) L) of fluorescein, YOYO-intercalated T7-phage DNA, 100-nm-diameter unilamellar liposomes, or fluorescent latex spheres could be injected into the intraliposomal compartment. We also demonstrate initiation of a chemical intercalation reaction between T2-phage DNA and YOYO-1 by dual injection into a single giant unilamellar liposome. The method was also successfully applied for loading of single cultured cells.

  • 9. Lundqvist, J A
    et al.
    Sahlin, F
    Aberg, M A I
    Strömberg, Anette
    Göteborg University, Sweden.
    Eriksson, P S
    Orwar, O
    Altering the biochemical state of individual cultured cells and organelles with ultramicroelectrodes1998In: Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, E-ISSN 1091-6490, Vol. 95, no 18, p. 10356-10360Article in journal (Other academic)
    Abstract [en]

    We describe an efficient technique for the selective chemical and biological manipulation of the contents of individual cells. This technique is based on the electric-field-induced permeabilization (electroporation) in biological membranes using a low-voltage pulse generator and microelectrodes. A spatially highly focused electric field allows introduction of polar cell-impermeant solutes such as fluorescent dyes, fluorogenic reagents, and DNA into single cells. The high spatial resolution of the technique allows for design of, for example, cellular network constructions in which cells in close contact with each other can be made to possess different biochemical, biophysical, and morphological properties. Fluorescein, and fluo-3 (a calcium-sensitive fluorophore), are electroporated into the soma of cultured single progenitor cells derived from adult rat hippocampus. Fluo-3 also is introduced into individual submicrometer diameter processes of thapsigargin-treated progenitor cells, and a plasmid vector cDNA construct (pRAY 1), expressing the green fluorescent protein, is electroporated into cultured single COS 7 cells, At high electric field strengths, observations of dye-transfer into organelles are proposed.

  • 10.
    Olofsson, Jessica
    et al.
    Chalmers University of Technology, Gothenburg, Sweden .
    Levin, Mikael
    Cellectricon AB, Gothenburg, Sweden.
    Strömberg, Anette
    Cellectricon AB, Gothenburg, Sweden.
    Weber, Stephen
    University of Pittsburgh, United States.
    Ryttsén, Frida
    Cellectricon AB, Gothenburg, Sweden.
    Orwar, Owe
    Chalmers University of Technology, Gothenburg, Sweden .
    Scanning electroporation of selected areas of adherent cell cultures2007In: Analytical Chemistry, ISSN 0003-2700, E-ISSN 1520-6882, Vol. 79, no 12, p. 4410-4418Article in journal (Refereed)
    Abstract [en]

    We present a computer-controlled scanning electroporation method. Adherent cells are electroporated using an electrolyte-filled capillary in contact with an electrode. The capillary can be scanned over a cell culture and locally deliver both an electric field and an electroporation agent to the target area without affecting surrounding cells. The instantaneous size of the targeted area is determined by the dimensions of the capillary. The size and shape of the total electroporated area are defined by these dimensions in combination with the scanning pattern. For example, striped and serpentine patterns of electroporated cells in confluent cultures can be formed. As it is easy to switch between different electroporation agents, the method is suitable for design of cell cultures with complex composition. Finite element method simulations were used to study the spatial distributions of the electric field and the concentration of an electroporation agent, as well as the fluid dynamics related to scanning and flow ofelectroporation agent from the capillary. The method was validated for transfection by introduction of a 9-base-pair-long randomized oligonucleotide into PC12 cells and a pmaxGFP plasmid coding for green fluorescent protein into CHO and WSS cells.

  • 11.
    Sjödin, Carina
    et al.
    Mälardalen University, School of Innovation, Design and Engineering, Innovation and Product Realisation.
    Strömberg, Anette
    Mälardalen University, School of Innovation, Design and Engineering, Innovation and Product Realisation.
    Sannö, Anna
    Volvo Construction Equipment, Technology Center Dept CE42700, 631 85 Eskilstuna, Sweden.
    Stec, Michael
    Volvo Construction Equipment, Technology Center Dept CE42700, 631 85 Eskilstuna, Sweden.
    Collaborative foresight for sustainable innovation2022In: LUT Scientific and Expertise Publications, 2022Conference paper (Other academic)
    Abstract [en]

    Openness, broad involvement and inclusion of different perspectives are considered a useful strategy for successful innovation. We suggest this is valid also for foresight practice as a part of an innovation process. In this paper, collaborative signal scanning regarding sustainability, act as the foundation for an intervention in an interactive research study discussing how to distribute and improve foresight practice, based on broad involvement for sustainable innovation? This research was performed as a university industry collaboration. The intervention consisted of two parts: moderated networking meetings with the purpose of sharing and reflecting on weak signals about sustainability and access to a learning module consisting of practical and theoretical material on corporate foresight, accessible via a digital learning platform. Participants express new insights, changed habits both in private and professional situations, and a strong incentive to pursue this work. The lack of time is a hinder for the individuals.

  • 12.
    Strömberg, Anette
    University of Gothenburg.
    Manipulating and Mimicking Single-Cell Compartments Using Liposome Chemistry and Miniaturized Biomembrane Electropermeabilization2001Doctoral thesis, comprehensive summary (Other academic)
  • 13.
    Strömberg, Anette
    Mälardalen University, School of Innovation, Design and Engineering, Innovation and Product Realisation.
    Method and apparatus for manipulation of cells and cell like structures using focused electric fields in microfluidic systems and use thereof2006Patent (Other (popular science, discussion, etc.))
  • 14.
    Strömberg, Anette
    et al.
    Göteborg University, Sweden.
    Karlsson, A
    Ryttsen, F
    Davidson, M
    Chiu, D T
    Orwar, O
    Microfluidic device for combinatorial fusion of liposomes and cells2001In: Analytical Chemistry, ISSN 0003-2700, E-ISSN 1520-6882, Vol. 73, no 1, p. 126-130Article in journal (Refereed)
    Abstract [en]

    We describe an electrofusion-based technique for combinatorial synthesis of individual liposomes. A prototype device with containers for liposomes of different compositions and a fusion container was constructed. The sample containers had fluid contact with the fusion container through microchannels. Optical trapping was used to transport individual liposomes and cells through the microchannels into the fusion container. In the fusion container, selected pairs of liposomes were fused together using microelectrodes. A large number of combinatorially synthesized Liposomes with complex compositions and reaction systems can be obtained from small sets of precursor liposomes. The order of different reaction steps can be specified and defined by the fusion sequence. This device could also facilitate single cell-cell electrofusions (hybridoma production). This is exemplified by fusion of transported red blood cells.

  • 15.
    Strömberg, Anette
    et al.
    Göteborg University, Sweden.
    Ryttsen, F
    Chiu, D T
    Davidson, M
    Eriksson, P S
    Wilson, C F
    Orwar, O
    Zare, R N
    Manipulating the genetic identity and biochemical surface properties of individual cells with electric-field-induced fusion2000In: Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, E-ISSN 1091-6490, Vol. 97, no 1, p. 7-11Article in journal (Refereed)
    Abstract [en]

    A method for cell-cell and cell-liposome fusion at the single-cell level is described. Individual cells or liposomes were first selected and manipulated either by optical trapping or by adhesion to a micromanipulator-controlled ultramicroelectrode. Spatially selective fusion of the cell-cell or cell-liposome pair was achieved by the application of a highly focused electric field through a pair of 5-mu m o.d. carbon-fiber ultramicroelectrodes. The ability to fuse together single cells opens new possibilities in the manipulation of the genetic and cellular makeup of individual cells in a controlled manner, In the study of cellular networks, for example, the alteration of the biochemical identity of a selected cell can have a profound effect on the behavior of the entire network. Fusion of a single liposome with a target cell allows the introduction of the liposomal content into the cell interior as well as the addition of lipids and membrane proteins onto the cell surface. This cell-liposome fusion represents an approach to the manipulation of the cytoplasmic contents and surface properties of single cells. As an example, we have introduced a membrane protein (gamma-glutamyltransferase) reconstituted in liposomes into the cell plasma membrane.

  • 16. Wilson, C F
    et al.
    Simpson, G J
    Chiu, D T
    Strömberg, Anette
    Göteborg University, Sweden.
    Orwar, O
    Rodriguez, N
    Zare, R N
    Nanoengineered structures for holding and manipulating liposomes and cells2001In: Analytical Chemistry, ISSN 0003-2700, E-ISSN 1520-6882, Vol. 73, no 4, p. 787-791Article in journal (Refereed)
    Abstract [en]

    We describe the fabrication of nanoengineered holding pipets with concave seating surfaces and fine pressure control. These pipets were shown to exhibit exceptional stability in capturing, transporting, and releasing single cells and liposomes 1-12 mum in diameter, which opens previously inaccessible avenues of research. Three specific examples demonstrated the, utility and versatility of this manipulation system. In the first, carboxyrhodaminie was selectively incorporated into individual cells by electroporation, after which nearly all the medium (hundreds of microliters) surrounding the docked and tagged cells was rapidly exchanged (in seconds) and the cells were subsequently probed by laser-induced fluorescence (LIF). In the second study, a single liposome containing carboxyrhodamine was transported to a dye-free solution using a transfer pipet, docked to a holding pipet, and held firmly during physical agitation and interrogation by LIF. In the third study, pairs of liposomes were positioned between two microelectrodes, held in contact, and selectively electrofused and the resulting liposomes undocked intact.

1 - 16 of 16
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf