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  • 1.
    Martin, L M
    et al.
    Karolinska Institutet, Stockholm, Sweden.
    Lindblom, B
    Sahlgrenska University Hospital, Göteborg, Sweden.
    Gedda, U K
    St. Erik Eye Hospital, Stockholm, Sweden.
    Concordance between results of optic disc tomography and high-pass resolution perimetry in glaucoma2000Inngår i: Journal of glaucoma, ISSN 1057-0829, E-ISSN 1536-481X, Vol. 9, nr 1, s. 28-33Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    PURPOSE: To evaluate concordance between results obtained with the Heidelberg Retina Tomograph (HRT) (Heidelberg Engineering GmbH, Heidelberg, Germany) and those obtained with the high-pass resolution perimeter (HRP) in glaucoma diagnosis. METHODS: A total of 217 patients from the glaucoma services at St. Erik Eye Hospital, Stockholm, Sweden (n = 107) and Sahlgrenska University Hospital, Göteborg, Sweden (n = 110) were included in the study. All patients were examined because of known or suspected glaucoma in at least one eye. The conventional indices presented by the instruments were used, i.e., glaucoma index from the HRT (negative values = abnormal, positive = normal) and combined deviation (upper normal limit 2.1 dB) from the HRP. RESULTS: The concordance regarding the classification of normal or glaucomatous by the two instruments was 71% (153/217 eyes). The HRT indicated glaucoma but HRP findings were normal in 47 patients, and the reverse occurred in 17 patients. There was a significant difference in optic disc area between patients with abnormal HRT findings and normal HRP findings and in patients with normal HRT findings and abnormal HRP findings. The concordance could not be improved by adjusting for disc size. The correlation between combined deviation on HRP and the HRT glaucoma index was r = -0.53. CONCLUSION: A significant correlation was found between the combined index given by HRP and the HRT glaucoma index in 217 patients examined for known or suspected glaucoma. Discordant findings were observed in 64 patients; in 22 this discordance was explained by the influence of disc size. No other reasons for differences in examination results could be detected.

  • 2.
    Martin, Lene
    et al.
    Stockholm University, Sweden.
    Wanger, P
    St. Erik Eye Hospital, Stockholm, Sweden.
    Five-year follow-up of treated patients with glaucoma using resolution perimetry1998Inngår i: Journal of glaucoma, ISSN 1057-0829, E-ISSN 1536-481X, Vol. 7, nr 1, s. 22-6Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    PURPOSE: The authors describe high-pass resolution perimetry findings during the first five years of antiglaucoma treatment. PATIENTS AND METHODS: Thirty-seven patients were examined six times, once a year for five years, with best corrected visual acuity, applanation tonometry, slitlamp examination, funduscopy, and high-pass resolution perimetry. Twenty-nine of these were treated for glaucoma and eight followed for ocular hypertension without treatment. RESULTS: The resolution thresholds in the treated group improved during the first two years and deteriorated after that back to baseline level. Regarding individual patients, the visual fields were improved in 4, unchanged in 16, and deteriorated in 13 of the 29 treated glaucoma patients at the end of the study period. CONCLUSIONS: Resolution visual fields showed initial improvement and subsequent deterioration in treated patients with early glaucoma. The conventional therapy, aiming at reducing intraocular pressure, appeared to postpone visual field decay for at least five years in about 50% of the patients.

  • 3.
    Martin, Lene
    et al.
    Karolinska Institutet, Stockholm, Sweden.
    Wanger, Peter
    St. Erik's Eye Hospital, Sweden.
    New perimetric techniques: a comparison between rarebit and frequency doubling technology perimetry in normal subjects and glaucoma patients2004Inngår i: Journal of glaucoma, ISSN 1057-0829, E-ISSN 1536-481X, Vol. 13, nr 4, s. 268-72Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    PURPOSE: To compare rarebit microdot perimetry (RB) with frequency doubling technology (FDT) perimetry in normal subjects and a group of patients with ocular hypertension or glaucoma, with age-matched controls. MATERIALS AND METHODS:: Eighty-one subjects (age 17-88 years) were examined. Twenty-seven of these were patients, aged 50 to 88 years, with ocular hypertension or suspected/manifest glaucoma in at least one eye. All subjects were examined with the RB and FDT perimetry, using the standard procedures, recommended by the respective manufacturer. RESULTS: All patients were able to perform the RB perimetry, but three patients could not perceive the strongest FDT stimulus. The concordance in RB and FDT classifications as normal/outside normal limits was 96% (Cohen's kappa = 0.90). A curvilinear (quadratic) relationship (Rsq = 0.75) was found between RB hit rate and FDT MD. All patients, who could perform both examinations, preferred the RB perimetry. CONCLUSION: In the current study, the information from the RB and FDT perimetry was almost completely equivalent. However, RB perimetry was preferred by the patients and seemed to have a larger dynamic range than FDT. The RB hit rate is apparently a straightforward and efficient measure of visual field function.

  • 4.
    Martin, Lene
    et al.
    Karolinska Institutet, Stockholm, Sweden.
    Wanger, Peter
    Karolinska Institutet, Stockholm, Sweden.
    Vancea, Lucian
    Sundsvall Hospital, Sundsvall, Sweden.
    Göthlin, Birgitta
    St Eriks Eye Hospital.
    Concordance of high-pass resolution perimetry and frequency-doubling technology perimetry results in glaucoma: no support for selective ganglion cell damage.2003Inngår i: Journal of glaucoma, ISSN 1057-0829, E-ISSN 1536-481X, Vol. 12, nr 1, s. 40-44Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    PURPOSE: To compare the results of frequency-doubling technology perimetry (FDT), assumed to test the magnocellular visual pathway, and high-pass resolution perimetry (HRP), assumed to test the parvocellular visual pathway, in patients with ocular hypertension or glaucoma. PATIENTS AND METHODS: Forty-eight consecutive patients with glaucoma or ocular hypertension, covering the entire range of optic nerve function from normal to severely damaged, were examined on the same day using FDT and HRP. RESULTS: There was a linear correlation between both global and local indices in FDT and HRP (r = -0.84 P<0.0001 and r = 0.8 P<0.001, respectively). The HRP and FDT classifications agreed in 32 of the 48 (67%) eyes (Cohen kappa = 0.5). There was no significant difference between the ability of the different techniques to detect abnormality. CONCLUSION: The observations in the present study indicate either that both cell populations are similarly affected by glaucomatous damage or that both methods measure activity in the same cell populations.

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