The challenge for every multinational manufacturing company with the ambition to implement the lean production concept is how to implement it worldwide within its global manufacturing footprint. There are many decisions that need to be taken from a company group perspective when planning and implementing a lean program. These concern the level of standardization on principles and tools, how to structure and organize additional resources, how to share experiences within the organization, and how to sustain the effort. These factors are elaborated in this chapter from a factory perspective based on the presentation of the lean journey of Gyproc AB, a process industry company within the Gypsum part of the large Saint Gobain group. The company has worked for about ten years with implementing world-class manufacturing and has extensive experience of the issues of starting-up and sustaining the lean-based concept.