The chapter elaborates how workplace social relations influence practice in the return to work process. The social conditions in which the return to work process is embedded, and the way social interaction and relations between the sick-listed worker and other workplace actors (supervisor and coworkers) evolve, have only been researched to a limited extent. In this book chapter, we will discuss critical new dimensions of social relations research in the field of return to work that can “make” or “break” a workplace return to work process. These critical new dimensions highlight the importance of viewing return to work as a dynamic process over time, where supervisors and coworkers display shifting roles depending on phases of the process. The chapter conveys new dimensions of social relations, acknowledging the positive contribution of coworker efforts in the process, which may have an important impact on workplace-based return to work interventions.