Seventeen subjects with amblyopia due to strabismus and anisometropia were examined using high-pass resolution perimetry. In addition to the standard technique, testing the 5-30 degrees visual field, an optional program testing the central 4 degrees visual field was used. Threshold elevation was confined to the central 4 degrees visual field and strongly correlated with visual acuity, expressed as minimum angle of resolution. Standard high-pass resolution perimetry did not reveal any significant abnormalities in the amblyopic subjects. In conclusion, the technique is useful for the diagnosis of ocular or neurologic disorders also in subjects with a high degree of amblyopia.