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State-of-the-art breath analysers require a prolonged expiration into a mouthpiece to obtain the accuracy required for evidential testing and screening of the alcohol concentration. This requirement is unsuitable for breath analysers used as alcolock owing to their frequent use and the fact that the majority of users are sober drivers; as well as for breath testing in uncooperative persons.

This thesis presents a method by which breath alcohol analysis can be improved, using carbon dioxide (CO₂) as the tracer gas, offering quality control of the breath sample, enabling the mouthpiece to be eliminated, and bringing about a significant reduction in the time and effort required for a breath alcohol screening test. With simultaneous measurement of the ethanol and the CO₂ concentrations in the expired breath, the end-expiratory breath alcohol concentration (BrAC) can be estimated from an early measurement, without risk of underestimation.

Comparison of CO₂ and water (H₂O) as possible tracer gases has shown that the larger intra- and inter-individual variations in the (end-expiratory) concentration is a drawback for CO₂ whereas the advantages are a low risk of underestimation of the BrAC, and the limited influence from ambient conditions on the measured CO₂ concentration. The latter is considered to be of importance because the applications likely imply that the breath tests will be conducted in an uncontrolled environment, e.g., in a vehicle or ambulance. In emergency care, the measurement of the expired CO₂ concentration also provides the physicians with information about the patient's respiratory function.

My hope and belief, is that with a more simple, reliable and, user-friendly test procedure, enabled with the simultaneous measurement of the CO₂ in the breath sample, the screening for breath alcohol will increase. An increased number of breath alcohol analysers installed as alcolocks and more breath alcohol tests conducted in emergency care, is likely to save lives and diminish the number and severity of injuries.