Meeting customer demands require manufacturing systems with a high degree of flexibility, low-cost/low-volume manufacturing skills, as well as short delivery times. On top of these challenges, there is a gigantic need within industry for technologies and strategies that will reduce CO(2) emissions globally. In this challenging environment there is a need to identify and develop new and improved manufacturing capabilities within the manufacturing industry. The Factory-in-a-Box concept consists of standardized production modules that are e.g. installed in a container and transported by truck or by train. The concept has been developed, exemplified and realized in five industrial demonstrators developed by researchers together with competitive manufacturing companies in Sweden such as ABB Robotics, Bombardier and Pharmadule. The objective of this paper is to discuss the possibility of realizing a Product Service System (PSS) using the results from the Factory-in-a-Box project.