The aim of this work is to investigate the properties and classification of an interesting class of 4-dimensional 3-Hom-Lie algebras with a nilpotent twisting map alpha and eight structure constants as parameters. Derived series and central descending series are studied for all algebras in this class and are used to divide it into five non-isomorphic subclasses. The levels of solvability and nilpotency of the 3-Hom-Lie algebras in these five classes are obtained. Building upon that, all algebras of this class are classified up to Hom-algebra isomorphism. Necessary and sufficient conditions for multiplicativity of general (n+1)-dimensional n-Hom-Lie algebras, as well as for algebras in the considered class, are obtained in terms of the structure constants and the twisting map. Furthermore, for some algebras in this class, it is determined whether the terms of the derived and central descending series are weak subalgebras, Hom-subalgebras, weak ideals, or Hom-ideals.