In a review and theoretical analysis, Quality Function Deployment, Design Thinking and complementary methodologies have been assessed as supporting instruments in the development of non-assembled products. The findings demonstrate that QFD and DT characteristics substantially differ and that DT lacks many aspects of importance for process-industrial application. However, the results show that the methodologies are complementary in use; thus, an indepth knowledge of both methodologies could create a company competitive advantage in product innovation. Companies in the process industries are thus advised to use the results as a guiding framework for methodology selection and use in the different parts of the product innovation work process.