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Patient Perspectives on the Value of Patient Preference Information in Regulatory Decision Making: A Qualitative Study in Swedish Patients with Rheumatoid Arthritis
Uppsala universitet, Centrum för forsknings- och bioetik, Sweden.ORCID iD: 0000-0002-5865-5590
Uppsala universitet, Centrum för forsknings- och bioetik, Sweden.
Uppsala universitet, Centrum för forsknings- och bioetik, Sweden.
Uppsala universitet, Centrum för forsknings- och bioetik, Sweden.
2019 (English)In: Patient, ISSN 1178-1653, E-ISSN 1178-1661, Vol. 12, no 3, p. 297-305Article in journal (Refereed) Published
Abstract [en]

Background

There is increasing interest in involving patient preferences for benefits and risks in regulatory decision making. Therefore, it is essential to identify patient perspectives regarding the value of patient preference information (PPI).

Objectives

The aim of this study was to explore how patients with rheumatoid arthritis (RA) value the use of PPI in regulatory decision making regarding medical products.

Methods

Regulators and patients with RA were interviewed to gather initial insights into opinions on the use of PPI in regulatory decisions regarding medical products. The interviews were used to draft and validate the interview guide for focus groups with patients with RA. Participants were purposively sampled in collaboration with the Swedish Rheumatism Association in Stockholm and Uppsala. Each focus group consisted of three to six patients (18 in total). All interviews were audio-recorded, transcribed verbatim, and analysed using content analysis.

Results

According to the participants, PPI could lead to regulators considering patients’ needs, lifestyles and well-being when making decisions. PPI was important in all stages of the medical product lifecycle. Participants reported that, when participating in a preference study, it is important to be well-informed about the use of the study and the development, components, administration, and risks related to the medical products.

Conclusions

Patients thought PPI could be valuable to consider in regulatory decisions. It is essential for patients to be well-informed when asked for their preferences. Research on information materials to inform patients in preference studies is needed to increase the value of PPI in regulatory decision making.

Place, publisher, year, edition, pages
2019. Vol. 12, no 3, p. 297-305
National Category
Medical Ethics
Identifiers
URN: urn:nbn:se:mdh:diva-62344DOI: 10.1007/s40271-018-0344-2ISI: 000468375300003PubMedID: 30443897Scopus ID: 2-s2.0-85056714188OAI: oai:DiVA.org:mdh-62344DiVA, id: diva2:1753468
Funder
Riksbankens Jubileumsfond, M13-0260:1Available from: 2023-04-27 Created: 2023-04-27 Last updated: 2023-10-23Bibliographically approved

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Schölin Bywall, KarinVeldwijk, JorienHansson, Mats G.Kihlbom, Ulrik

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