Background: Patients with a non-European cultural background may experience thatpalliative care does not meet their cultural needs. Due to communication difficulties such aslanguage differences and other cultural factors that may affect communication, patients mayexperience these as an obstacle to having their cultural needs fulfilled. Palliative care shouldbe based on a holistic view of the human being, where mental, social and existential needsneed to be accounted for. The theory of transcultural care aims to understand the humanperspective from the persons cultural perspective. Aim: To describe nurses' experiences ofproviding palliative care to patients with a non-European cultural background. Method: Aqualitative systematic literature study with a descriptive synthesis. Result: Based on theanalysis, two themes emerged; to meeting cultural barriers and to face another culture.Based on the first theme to meeting cultural barriers, three sub-themes emerged, linguisticdifferences, finding good ways to communicate and the lack of cultural competence. Basedon the second theme, to face another culture, two sub-themes emerged, meeting the patient'scultural needs and taking into account the human being regardless of cultural background.Conclusion: The nurses experienced several challenges in creating a culturally adaptedpalliative care for patients with a non-European cultural background. Nurses experiencedthese challenges due to lack of knowledge and lack of understanding of the patient's culturalneeds.