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Some patients in nursing homes require extra attention to enable staff todetect and manage deterioration at an early stage. Nursing skills are vital to makesystematic observations and assessments of a patient’s condition. It is challenging fornurses in nursing homes to make professional decisions without being able to consultother nurses. To improve the quality and safety of health care for patients and theirrelatives, the focus must be on working to ensure patient safety in nursing homes.Simulation-based learning can be one way to increase reflection on patient safety anddevelop health professionals’ knowledge, skills and attitudes, while protecting patientsfrom unnecessary risks. Simulation-based learning as a method in medical educa-tion offers activities that mimic a clinical environment, where students can practiceprocedures and decision-making and where their critical thinking can be enhancedthrough role-play, videos or simulators. While simulation often takes place in a sim-ulation center, in situ simulation refers to a learning activity that takes place in par-ticipants’ everyday work environment where they actually provide patient care. Inthis chapter, we aim to describe nurses’ experiences of in situ simulation and theirsubsequent reflections on patient safety in nursing homes. Data were collected fromtwo focus groups with 5–6 nurses per group. The transcribed material was analyzedusing qualitative content analysis, and two categories were identified that describedthe nurses’ experiences: “to doubt oneself ” and “being dependent on others”.