Ensuring healthy lives and promoting a healthy well-being for all at all ages are listed as some of the goals in Agenda 2030 for Sustainable Development. Considering that noncommunicable diseases (NCDs) are the leading cause of death worldwide, reducing the mortality of NCDs is an important target. To reach this goal, means for detecting and reacting to warning signals are necessary. Here, remote health monitoring in real time has great potential. This article provides a systematic review of the use of wearable sensors for the monitoring and prevention of NCDs. In addition, this article not only provides in-depth information about the retrieved articles, but also discusses examples of studies assessing warning signals that may result in serious health conditions, such as stroke and cardiac arrest, if left untreated. One finding is that even though many good examples of wearable sensor systems for monitoring and controlling NCDs are presented, many issues also remain to be solved. One major issue is the lack of testing on representative people from a sociodemographic perspective. Even though substantial work remains, the use of wearable sensor systems has a great potential to be used in the battle against NCDs by providing the means to diagnose, monitor and prevent NCDs.