The family of process industries embodies multiple industrial sectors and make up an important part of the entire manufacturing industries of particular importance for late-industrializing countries. In a review of the extant literature on product innovation work processes and best practice innovation of non-assembled products, an integrated conceptual framework has been developed. The novel framework is proposed to guide and invigorate company development and design of individualized product innovation work processes more adapted to process-industrial contextual and innovation conditions. Due to the coupling between products and the production systems in the process industries, it is concluded that development of new products must be better integrated with the development of necessary production capabilities in an end-to-end work process perspective. Research on fuzzy front-end of process-industrial product innovation has been amalgamated but it is demonstrated that more attention should be paid to industrialization and market launch; here denominated the bumpy back-end.