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Diagnostic accuracy of the Montgomery-Asberg Depression Rating Scale parent report among adolescent psychiatric outpatients
Uppsala Univ, Vastmanlands Cty Hosp, Clin Res Ctr, Vasteras, Sweden..
Uppsala Univ, Vastmanlands Cty Hosp, Clin Res Ctr, Vasteras, Sweden..
Uppsala Univ, Vastmanlands Cty Hosp, Clin Res Ctr, Vasteras, Sweden..
Uppsala Univ, Akad Sjukhuset, Dept Neurosci, Uppsala, Sweden..
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2018 (English)In: Nordic Journal of Psychiatry, ISSN 0803-9488, E-ISSN 1502-4725, Vol. 72, no 3, p. 184-190Article in journal (Refereed) Published
Abstract [en]

Background: The diagnostic accuracy of the parent report of the Montgomery-angstrom sberg Depression Rating Scale (MADRS-P) for the screening of major depressive disorder (MDD) in adolescents has not been evaluated.Aim: The aim was to explore the psychometric properties and diagnostic accuracy of the MADRS-P in general child and adolescent psychiatric outpatient services in Sweden.Method: The study was a validation and a diagnostic accuracy study. Consecutive adolescent psychiatric patients (n=101, 45 males, mean age 15 years) were assessed with a diagnostic interview, the Kiddie Schedule of Affective Disorders and Schizophrenia for School-Age Children - Present and Lifetime version (K-SADS-PL), as a reference test. Thereafter, their parents reported on the MADRS-P. Both categorical MDD diagnoses and dimensional MDD symptom severity scores were obtained from the K-SADS-PL.Results: The internal consistency of the MADRS-P, measured with Cronbach's alpha, was 0.846. The concurrent validity, assessed by Spearman's rho as a correlation between the K-SADS MDD symptom severity score and the MADRS-P score, was 0.580. The area under the curve in a receiver operating characteristic analysis for all participants was 0.786 (95% confidence interval 0.694-0.877, p<.001). At a cut-off of 10, sensitivity was 0.86, specificity 0.54, positive predictive value 0.59 and negative predictive value 0.84.Conclusions: The parent-rated MADRS-P showed similar psychometric properties as previously shown for the self-rated MADRS-S in adults. Although the MADRS-P has acceptable diagnostic accuracy for screening for MDD in adolescents in a general psychiatric setting, it cannot be used alone for diagnosing MDD.

Place, publisher, year, edition, pages
TAYLOR & FRANCIS LTD , 2018. Vol. 72, no 3, p. 184-190
Keywords [en]
Depression, questionnaire, validation study, adolescents, parents
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:mdh:diva-51988DOI: 10.1080/08039488.2017.1414873ISI: 000424948600005PubMedID: 29258381Scopus ID: 2-s2.0-85038370961OAI: oai:DiVA.org:mdh-51988DiVA, id: diva2:1484427
Available from: 2020-10-28 Created: 2020-10-28 Last updated: 2021-01-20Bibliographically approved

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Nilsson, Kent W.

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