mdh.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Folate and vitamin B-12 concentrations are associated with plasma DHA and EPA fatty acids in European adolescents: the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study
Univ Zaragoza, Inst Invest Sanitaria Aragon IIS, Growth Exercise Nutr & Dev GENUD Res Grp, IA2, E-50009 Zaragoza, Spain.;Inst Salud Carlos III, Red Salud Maternoinfantil Desarrollo SAMID, C Monforte de Lemos 3-5,Pabellon 11,Planta 0, Madrid 28029, Spain..
Univ Ghent, Univ Hosp, Dept Publ Hlth, De Pintelaan 185,Entrance 42,Bldg K3,4th Floor, B-9000 Ghent, Belgium.;IARC, 150 Cours Albert Thomas, F-69372 Lyon 08, France..
Univ Politecn Madrid, Dept Hlth & Human Performance, ImFINE Res Grp, C Martin Fierro 7, E-28040 Madrid, Spain.;Inst Salud Carlos III, Ctr Invest Biomed Red Fisiopatol Obesidad & Nutr, C Monforte de Lemos 3-5,Pabellon 11,Planta 0, Madrid 28029, Spain..
Univ Zaragoza, Inst Invest Sanitaria Aragon IIS, Growth Exercise Nutr & Dev GENUD Res Grp, IA2, E-50009 Zaragoza, Spain..
Show others and affiliations
2017 (English)In: British Journal of Nutrition, ISSN 0007-1145, E-ISSN 1475-2662, Vol. 117, no 1, 124-133 p.Article in journal (Refereed) Published
Abstract [en]

This study aimed to examine the association between vitamin B-6, folate and vitamin B-12 biomarkers and plasma fatty acids in European adolescents. A subsample from the Healthy Lifestyle in Europe by Nutrition in Adolescence study with valid data on B-vitamins and fatty acid blood parameters, and all the other covariates used in the analyses such as BMI, Diet Quality Index, education of the mother and physical activity assessed by a questionnaire, was selected resulting in 674 cases (43% males). B-vitamin biomarkers were measured by chromatography and immunoassay and fatty acids by enzymatic analyses. Linear mixed models elucidated the association between B-vitamins and fatty acid blood parameters (changes in fatty acid profiles according to change in 10 units of vitamin B biomarkers). DHA, EPA) and n-3 fatty acids showed positive associations with B-vitamin biomarkers, mainly with those corresponding to folate and vitamin B12. Contrarily, negative associations were found with n-6: n-3 ratio, trans-fatty acids and oleic: stearic ratio. With total homocysteine (tHcy), all the associations found with these parameters were opposite (for instance, an increase of 10 nmol/l in red blood cell folate or holotranscobalamin in females produces an increase of 15.85 mu mol/l of EPA (P value < 0.01), whereas an increase of 10 nmol/l of tHcy in males produces a decrease of 2.06 mu mol/l of DHA (P value < 0.05). Positive associations between B-vitamins and specific fatty acids might suggest underlying mechanisms between B-vitamins and CVD and it is worth the attention of public health policies.

Place, publisher, year, edition, pages
CAMBRIDGE UNIV PRESS , 2017. Vol. 117, no 1, 124-133 p.
Keyword [en]
Fatty acids, B-vitamins, Adolescents, Europe
National Category
Health Sciences
Identifiers
URN: urn:nbn:se:mdh:diva-35125DOI: 10.1017/S0007114516004414ISI: 000395508700011PubMedID: 28098048Scopus ID: 2-s2.0-85009733703OAI: oai:DiVA.org:mdh-35125DiVA: diva2:1087263
Available from: 2017-04-06 Created: 2017-04-06 Last updated: 2017-04-06Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMedScopus
By organisation
Health and Welfare
In the same journal
British Journal of Nutrition
Health Sciences

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 4 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf